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Bence György, MD, PhD

Date of birth: 07.01.1985

Nationality: Hungarian

Researcher unique identifier(s): ORCID ID: 0000-0003-0766-6246

Google Scholar: https://scholar.google.com/citations?user=Uk-LWCcAAAAJ&hl=en

LinkedIn: https://www.linkedin.com/in/bence-györgy-04534528/

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Current position

from 07/2022

Eccellenza Assistant Professor​

from 02/2019

Group Leader, Institute of Molecular and Clinical Ophthalmology, Basel, Switzerland

Education

2009-2013

PhD, Molecular Genetics

Semmelweis University

Budapest, Hungary

 

During my PhD my research focused on extracellular vesicles, which are small membrane-bound particles, which contain materials from the secreting cells. 

PhD advisor: Prof. Buzás Edit Irén

2011-2014

Postdoctoral fellowship

Harvard Medical School

Massachusetts General Hospital

 

During my post-doctoral years, I developed exosome-associated AAV vectors and gene editing-based therapeutics for various neurosensory diseases.

Advisors: Profs. David Corey, Xandra Breakefield and Casey Maguire

2003-2009

MD

Semmelweis University

Budapest, Hungary

Summary of publications

  • Number of peer-reviewed publications: 42

  • Total number of impact factors: 236.79

  • Total number of citations: 8,800 (as of 03.10.2024)

  • h index: 28

Patents

  • Human cone photoreceptor optogenetic constructs, WO2024033837A1

  • Hybrid System for Efficient Gene Delivery to Cells of the Inner Ear, WO2017136764A1

  • Aav vectors encoding clarin-1 or gjb2 and uses thereof, WO2019200016A1

  • Methods and compositions for allele specific gene editing WO2020257514A1

Reviewing activities

  • Nature Neuroscience

  • Nature Biomedical Engineering

  • Nature Communications

  • Science Advances

  • American Journal of Human Genetics

  • Proceedings of the National Academy of Sciences of the United States of America

  • Molecular Therapy

  • Molecular Therapy Methods and Clinical Development

  • Molecular Therapy Nucleic Acids

  • CRISPR Journal

  • several other journals

Scientific Advisory Board

  • Swiss Expert Committee for Biosafety (SECB) - Gene Therapy Working Group 

  • Usher Syndrome Society

  • Save Sight Now Europe

  • Fondation Pour l’Audition

Highlighted Awards

  • Eccellenza Professorhip, SNF

  • RetinAward, Swiss Vitreoretinal Group

  • Excellence in Research Award, American Society of Gene and Cell Therapy

  • Edward R. and Anne G. Lefler Center Postdoctoral Fellowship

  • American Society of Gene and Cell Therapy, Outstanding Poster Award

  • Excellent PhD Student Award, Semmelweis University, Association of Friends

  • Faculty 1000 recommendation on the article: György et al. 2010 Blood

  • Excellent Student at the Semmelweis University

  • Hungarian National Fellowship (awarded by the Hungarian Government to undergraduate students with outstanding academic achievements)                        

Funding

ONGOING:

  • 2022-2027 Swiss National Science Foundation, Eccellenza, PCEFP3_202756, Precision Gene therapy for inherited blindness

  • 2021-2024 ERA-NET + EJP: Genetic therapy for EYS- and USH2A-associated retinal dystrophy (PI)

  • 2020-2024 Swiss National Science Foundation, NZX2080, Therapeutic RNA base editing for Stargardt disease, CHF 800K (PI)

  • RhyGaze AG - sponsored research agreement (PI)

​

PAST:

  • 2020-2022 Foundation Fighting Blindness, Prime editing for Usher Syndrome Type 2A, (PI)

  • 2020-2022 Developing a non-human primate model for Stargardt disease caused by the
    ABCA4 G1961E mutation (co-PI)

  • 2020-2023 BEAM Therapeutics, Collaboration Agreement (co-PI)

Selected Invited Talks

2023

  • Biomedical Research Seminar, Bonn, Germany

  • Weilburg, DFG Research priority programme 2127

  • University of California Irvine, Distinguished Speaker Series, Irvine, CA, USA

2022

  • Vision 360 KKL, 2021 Triemli Hospital Summer Symposium, Zurich, Switzerland;

  • Telethon Institute of Genetics and Medicine, Online Seminar;

  • Usher Symposium Paris, France

  • Swiss Society of Toxicology, Basel, Switzerland

2019

  • Rudbeck Seminar, Uppsala University, Uppsala, Sweden;

  • Semmelweis Synposium, Budapest, Hungary

2018

  • Bertarelli Symposium, Boston, MA, USA

2017

  • Lefler Symposium, Boston, MA, USA

2016

  • Bertarelli Symposium, Boston, MA, USA;

  • Microvesicle and Exosome Seminar Series, Boston, MA, USA

Media

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